diff --git a/qmk_cli/script_qmk.py b/qmk_cli/script_qmk.py
index 8d1f1b3..d7cf476 100644
--- a/qmk_cli/script_qmk.py
+++ b/qmk_cli/script_qmk.py
@@ -52,7 +52,19 @@ def main():
     if 'windows' in platform().lower():
         msystem = os.environ.get('MSYSTEM', '')
 
-        if 'mingw64' not in sys.executable or 'MINGW64' not in msystem:
+        # Assume the environment isn't workable by default
+        env_ok = False
+
+        # Check if we're using the mingw64/msys2 environment
+        if 'mingw64' in sys.executable and 'MINGW64' in msystem:
+            env_ok = True
+
+        # Check if we're using a `uv`-based environment
+        if '\\uv\\' in sys.executable or '/uv/' in sys.executable:
+            env_ok = True
+
+        # If none of the options above were true, then we're in an unsupported environment. Bomb out.
+        if not env_ok:
             print('ERROR: It seems you are not using the MINGW64 terminal.')
             print('Please close this terminal and open a new MSYS2 MinGW 64-bit terminal.')
             print('Python: %s, MSYSTEM: %s' % (sys.executable, msystem))